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AIM Proancynol® 2000 details

AIM Proancynol® 2000 details

antioxidantThe immune system is the group of organs, tissues, cells, and cell products, such as antibodies, that protects us from invaders. It differentiates self from nonself and neutralizes potentially pathogenic organisms or substances. For example, it protects us from bacteria, viruses, and cancer cells. The immune system is perhaps the most important body system when considering living well and maintaining good health. A healthy immune system is better equipped to meet challenges.

Free radicals

Oxygen is necessary for all living things. However, as the body creates energy at the cellular level, oxygen is metabolized, changing its structure. Oxygen atoms that lose an electron and are therefore unpaired are called free radicals. Free radicals are highly reactive and have the ability to bind to and destroy other cells. This combination of oxygen with another substance – oxidation – is the major source of free radical damage in the body. Some of the more destructive oxygen radicals are hydroxyl, superoxide, and hydrogen peroxide.

Although the majority of free radicals are produced in the body, they can also be derived from the environment, which increases the free radical load in the body. Sources of external free radicals include food additives and preservatives, fried and barbecued foods, rancid fats, cigarette smoke, air pollutants, cleaners, radiation, even sunlight.
Free radicals have been linked to many age-related diseases. These include cancer, heart attack, stroke, rheumatoid arthritis, cataracts, asthma, and Alzheimer’s disease.


While we all produce free radicals, we also have naturally occurring antioxidants, such as glutathione and superoxide dismutase, that fight free radicals and protect us from age-related diseases. However, the number of antioxidants we produce diminishes as we age, and we have so many free radicals to contend with that our own supply often isn’t enough.

Green tea

Green tea, unlike black tea, is made from leaves that are not fermented before they are dried. The primary constituents in green tea thought to provide the most health benefits are the polyphenols. Members of the flavonoid family, polyphenols are catechins made of several ringlike structures. Four are of particular interest: epicatechin, epigallocatechin, epicatechin gallate, and epigallocatechin gallate, the most potent.

In laboratory studies presented at a September 1997 meeting of the American Chemical Society, epigallocatechin gallate proved to be 100 times more effective at neutralizing free radicals than vitamin C and 25 times more effective than vitamin E.

Research does suggest that this antioxidant power may translate into helping to maintain immunity. In animal studies conducted in Japan in the early 1990s, green tea polyphenols increased activation of macrophages, B lymphocytes, T lymphocytes, and natural killer cells. All of these are white blood cells.

Studies indicate that green tea also helps lower blood pressure and cholesterol levels, helps reduce the risk of some forms of cancer, and helps reduce the formation of dental plaque. A recent study affirms that green tea is helpful with bone mineralization and therefore osteoporosis.

Green tea also contains oligomers of proanthocyanidins (OPCs), also in the flavonoid family, that have been shown to have positive effects on blood vessels.


Rosemary is increasingly under scrutiny for its antioxidant properties. Recent studies show that rosemary extract, and its constituents carnosol and ursolic acid, enhances the activity of enzymes that can detoxify carcinogens: animal studies show that the extract results in an increase in glutathione-S-transferase, one of these enzymes. Rosemary, an herb, also relaxes smooth muscle and may provide atherosclerotic protection. It is thought to have antifungal and antibacterial properties.

Grape seed

Like green tea, grape seeds contain the powerful antioxidant OPCs. Some studies indicate that OPCs are 20 times more powerful than vitamin C and 50 times more powerful than vitamin E. The two most common sources of OPCs are white pine bark and grape seed. Grape seeds contain 7 to 15 percent more OPCs than white pine bark and can be more potent.

In a review of the benefits of the OPCs found in grape seed extract, one study notes that the antioxidant activity of OPCs is generally credited for their other health benefits. The study notes that these include an antimutagenic effect; that is, they inhibit the mutation of DNA. The authors point out that chronic degenerative diseases are believed to be a result of environmental mutagens (substances that cause mutation). OPCs may be able to counter these mutagens.

OPCs also have “cosmetic” value. They protect collagen and elastin, which are an important part of the makeup of skin. It is the interlacing of collagen and elastin that gives skin its strength, elasticity, and smoothness. When these two substances are damaged and the skin loses elasticity, the result can be wrinkles. OPCs help restore damaged collagen and elastin and protect them against further damage.


Although little known, N-acetylcysteine (NAC) is a powerful antioxidant and a powerful tool in maintaining immunity. It has been used since the 1960s as a mucolytic – that is, a substance that breaks up mucus, especially in lung tissue. It also has a positive effect on toxic chemical and drug reactions, and has been used for years in hospital emergency rooms to counteract acetaminophen poisoning.

Clinical trials in Europe have indicated that NAC may also offer protection against the flu and flu-like symptoms. Other research indicates that it may enhance the production of human T cells, white blood cells with various immunity functions.

NAC is metabolized into compounds that can stimulate glutathione synthesis. The body produces glutathione, one of its most important and powerful antioxidants, to help it deal with the free radicals generated as part of its own metabolism.

Alpha-lipoic acid

When it was isolated 50 years ago, alpha-lipoic acid was identified as a vitamin. It has since been reclassified as an antioxidant, and can scavenge free radicals intracellularly and extracellularly. It is both fat- and water-soluble, which means that it can access all parts of our cells.
Numerous clinical trials have shown that supplementing with alpha-lipoic acid is beneficial in moderating blood sugar concentrations, symptoms of cardiovascular ailments, blurred vision, and liver complication.

Individuals who display limitations in moderating blood sugar concentrations often have a serious problem with glycation caused by higher than normal levels of blood sugar due to low insulin production or insulin resistance. Glycation happens when blood sugar reacts quickly and spontaneously with proteins to form damaging cross-linking. This cross-linking causes severe tissue damage and leads to kidney ailments, plaque buildup in the arteries, and retinopathy. Lipoic acid curtails glycation and enhances the transfer of blood sugar into the cells by stimulating insulin activity. One of the more severe complications of noncontrolled blood glucose levels is reduced circulation to the lower extremities. Studies show that patients suffering from symptoms of diabetic neuropathy improved significantly when they supplemented with 600 mg of lipoic acid daily.

Children treated with alpha-lipoic acid alone or in combination with vitamin E showed normalized organ function and less oxidative damage following radiation exposure in the Chernobyl incident.

Current research indicates that alpha-lipoic supplementation may help increase human T lymphocytes.

Alpha-lipoic acid has the ability to regenerate other antioxidants, including vitamins C and E, glutathione, and coenzyme Q10.

Antioxidant cycling

In antioxidant cycling, antioxidants work together for an enhanced, combined effect.

When the antioxidant vitamin E disables free radicals, it becomes a minor free radical. Both vitamin C and alpha-lipoic acid convert the radical form of vitamin E back to its antioxidant-self. However, when vitamin C recycles vitamin E, it changes to a free radical. Alpha-lipoic acid and glutathione can both “recycle” vitamin C back into a potent antioxidant.

Glutathione not only recycles vitamin C, but is the cells’ primary antioxidant. Maintaining high levels of glutathione is critical for life – low glutathione levels are a marker for death at an early age. Glutathione diminishes as we age and cannot be boosted significantly through supplements.

N-acetylcysteine manufactures glutathione, and alpha-lipoic acid regenerates glutathione, ensuring that the body has an adequate supply. Selenium is part of the enzyme glutathione peroxidase, which recycles glutathione.

OPCs also play a role in cycling as they sacrifice themselves in order to neutralize harmful free radicals. In doing so, they make it possible for vitamins C and E and selenium to do less “antioxidant” work, allowing these nutrients to perform their other functions in the body.

You can see how the ingredients found in AIM Proancynol® 2000 work together to provide optimum free radical protection.


Lycopene is a member of the carotenoid family. It is the pigment that gives fruits and vegetables its red color. Predominantly available in tomatoes, lycopene has been found to be twice as effective as beta-carotene and 100 times more effective than vitamin E in counteracting the dangerous free radical singlet oxygen. Lycopene has been found to be a more potent inhibitor of human cancer cells than all other carotenoids. A study in Europe found that there was a statistically significant association between high dietary lycopene and a 48 percent lower risk of cardiac disease.


Selenium is an antioxidant mineral. It works together with antioxidant enzymes to fight free radicals. Selenium activates the antioxidant enzyme glutathione peroxidase, which recycles glutathione.

Selenium improves white blood cell proliferation, and a selenium deficiency will result in a depressed immune system.

Selenium is reported to mimic the blood sugar regulatory functions of insulin in laboratory studies and to play a role in reducing the oxidative stress associated with diabetes. Selenium may also protect against cancers and cardiovascular disease by increasing HDL cholesterol levels.

The complete Immuno Health line consists of AIM Proancynol® 2000 and AIM Herbal Release®. Use these products to help yourself maintain immuno-respiratory health. Complimentary Products are AIM Bear Paw Garlic®, AIM GinkgoSense™, and AIMega™.

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AIM Proancynol® 2000                                      
60 softgel capsules


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Products of the AIM Companies™ have not been evaluated by the US Food and Drug Administration, FDA, and are not intended to diagnose, treat, cure, or prevent any disease, or illness. Results may vary per person. If you have Health concerns, see your Medical Practitioner, we do not give Medical Advise.

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