 AIM
CellSparc 360® in the UK
AIM CellSparc 360® combines CoQ10, tocotrienols, and fish oil to
provide you with the ultimate heart health product. These three ingredients
work together to ensure adequate energy production at the cellular level
and to maintain a healthy lipid profile. They truly provide a synergistic
effect for heart health.
You will find that AIM CellSparc 360® is superior
to other CoQ10 products on the market. AIM Members have a product that
combines 60 mg of CoQ10 with 100 mg of tocotrienols and 240 mg of fish
oil in a convenient softgel capsule. AIM CellSparc 360® contains no
artificial flavors or fillers, such as yeast, egg, or milk derivatives.
The softgel format also gives you increased bioavailability, stability,
purity, and consistency.Softgel capsules and absorption
A softgel delivery system can increase the absorption
of the product. A double-blind, controlled study shows that an oil-diluent
softgel CoQ10 formulation has an absorption rate almost three times
higher than that of a dry capsule CoQ10 formulation.
An oil-diluent softgel formulation resulted in a CoQ10
blood level of 265 percent over the base level, while a dry capsule
form of CoQ10 resulted in a blood level of 180 percent over the base
level.The dry capsule CoQ10 was absorbed at 3.4 micrograms per minute,
while the oil-diluent softgel CoQ10 was absorbed at 9.3 micrograms per
minute—a 273 percent difference. This greater bioavailability appears
to affect energy. Results show that 83 percent of those who used the
oil-diluent softgel form experienced more energy, compared to 30 percent
of those who used the dry capsule form.
 Coenzyme
Q10 and human nutrition
CoQ10 is found in the foods we eat, but not often
in large amounts. The best sources of CoQ10 are animal organs, some
types of fish, and vegetable oils such as soybean, rapeseed, and sesame.
It is found in lesser quantities in rice bran and wheat germ and in
soy and other beans. It is also found in vegetables, in particular spinach
and broccoli. CoQ10 is easily destroyed in the cooking process, and
much of the CoQ10 is removed in refined grains.
The body can also manufacture CoQ10 from other members
of the coenzyme Q (CoQ) family. CoQ10 is but one of ten, and possibly
more, members of the CoQ family. A meal consisting of shellfish, vegetables,
and mushrooms provides CoQ9 and CoQ7. To change these CoQs into CoQ10,
the liver breaks them down and reassembles them.
The creation of CoQ10 by the body is a complex process. At least three
different classes of starting molecules are required, at least 15 different
reactions are necessary (each begun by an enzyme), and many cofactor
substances are involved. Because all the component parts must be available
in sufficient quantities at the same time, CoQ10 is difficult for the
body to produce.Some of the essential cofactors are not created by
the body. A deficiency in any of these—vitamins B3, B5, B6, B12, C,
and folate—would make it difficult for the liver to produce enough CoQ10.
Unfortunately, the older you get, the less ability you have to produce
CoQ10 from other members of the CoQ family.
Our lives and environments also affect CoQ10 levels, in that stressful
lives and polluted environments can deplete CoQ10 from body tissue.According to Dr. Folkers, these factors—nutrient deficiencies,
age, stress, and pollution—could lead to a deficiency of CoQ10. By some
estimates, as many as 75 percent of people over age 50 in the United
States could be deficient in CoQ10.
The cardiovascular system consists of the heart and blood vessels. Heart
disease is the biggest killer in North America.
It includes structural or functional abnormalities of the heart, or
of the blood vessels supplying the heart, that impair its normal functioning.
Cholesterol contributes to build-up of plaque in the coronary arteries
that restricts blood flow to the heart, causing chest pain, and possibly
leading to heart attack and death.In addition to eating a nutritious diet and getting adequate exercise,
supplementation with coenzyme Q10 (CoQ10), tocotrienols, and fish oil
can help maintain heart health.Coenzyme Q10
All living cells require adenosine triphosphate (ATP)
to function. ATP represents a major source of stored energy in the body
and is responsible for many metabolic processes. CoQ10 is key in the
production of ATP.
CoQ10, or ubiquinone, is found throughout the body in cell membranes,
especially mitochondrial membranes, the areas of cells where food is
converted to energy. According to a 1990 article in the American Journal
of Cardiology, “Coenzyme Q10 is necessary for the mitochondria to perform
their functions and is essential for human life.” CoQ10 is most abundant
in the heart, lungs, liver, kidneys, and spleen.Without adequate levels of CoQ10, the body cannot
produce adequate levels of ATP. When you consider that the average person
uses 60 percent of his or her daily energy alone on base metabolism,
you can see how important CoQ10 is in ensuring that the body is able
to create enough energy for both its millions of everyday tasks and
its special energy needs.
In the mid-1960s, Japanese professor Yamamura was the first clinician
to use coenzyme Q7 (a compound related to CoQ10) in the treatment of
congestive heart failure. Since then, numerous clinical trials have
demonstrated the efficacy of CoQ10 in promoting cardiac health (Langsjoen
et al. 1994, Greenberg and Frishman 1990).A recent literature review looked at clinical trials,
articles, reviews, and letters published over the past 25 years in regard
to the role of CoQ10 in heart failure (Tran et al. 2001). The review
indicates that CoQ10 helps in how efficiently the heart pumps (ejection
fraction), how well the heart functions when it is made to work harder
(exercise tolerance), how much blood is pumped by the heart (stroke
volume), and how much blood the heart can pump in one minute (cardiac
output.)
The abstract of the review indicates that “the use of CoQ10 as adjuvant
therapy in patients with chronic heart failure may be supported.”Japanese researchers have also found that CoQ10 supplementation
prior to and immediately following open-heart surgery is highly beneficial
in preventing injuries related to reperfusion, restoring blood flow
to organs and tissues.
Studies also indicate that CoQ10 supplementation may decrease the amount
of medication used by heart disease patients, improve health as measured
by the New York Heart Association functional scale, improve overall
quality of life for heart patients, and act to maintain healthy blood
pressure levels.In addition to cardiac benefits, CoQ10 has been positively researched
with regard to periodontal disease, athletic performance (stressful
exercise reduces blood levels of CoQ10), muscular dystrophy, immunity
and infections, and HIV.
CoQ10 also seems to be a helpful secondary therapy in some cancers.
This is supported by research in regard to colon and prostatic cancers
and anecdotal reports in relation to pancreatic and lung cancer.Tocotrienols
Tocotrienols are a form of vitamin E. The term “vitamin
E” actually describes a group of eight fat-soluble compounds—alpha-,
beta-, delta-, and gamma-tocopherol and alpha-, beta-, delta-, and gammatocotrienol.
Usually, vitamin E is loosely used to refer to alpha-tocopherol.Tocotrienols are found in cereal seeds and rice bran,
and in palm and barley oils. Research indicates that tocotrienols have
antitumor and antioxidant properties and may reduce cholesterol.
In one study, 90 people with high cholesterol levels
followed the American Heart Association (AHA) Step-1 diet and took 100
mg of tocotrienols for a 35-day period.
This program reduced their total cholesterol levels
20 percent and their LDL cholesterol levels—the “bad cholesterol”—25
percent compared to their cholesterol levels at the beginning of the
study (Qureshi et al. 2002).
Another study (Serbinova and Packer 1994) shows that tocotrienols have
40 to 60 times more antioxidant ability than alpha-tocopherol—vitamin
E.
Fish oil
Diets high in saturated fats have been linked to high
blood cholesterol levels. Epidemiological studies have shown that in
populations where large amounts of fish are consumed, there is little
evidence of heart disease.
The U.S. Physicians’ Health Study found that men who consumed fish one
time per week cut their risk of sudden cardiac death by 52 percent compared
with men who ate fish less than one time per month (Albert, et al. 1998).A recent meta-analysis indicated that the use of dietary and supplemental
omega-3 polyunsaturated fatty acids reduces overall mortality, mortality
due to myocardial infarction, and sudden death in patients with coronary
heart disease (Bucher et al. 2002).Fish oil has also been found to help
reduce triglyceride—a type of fat—levels. High triglyceride levels are
a factor in heart disease. Fish oils are rich in eicosapentaenoic acid
(EPA) and docosahexaenoic acid (DHA), which are believed to decrease
the risk of thrombosis (blood clot) and lower blood pressure.
In addition to its health benefits, fish oil is used in AIM CellSparc
360® as a dissolvent for the CoQ10 and tocotrienols. Dr. Karl Folkers,
the doctor responsible for much of the research on CoQ10, recommended
that it be dissolved in oil. Because CoQ10 is fat-soluble, it requires
fat to be absorbed by the digestive tract. How to use AIM CellSparc 360®
- Suggested use: 1 to 2 softgel capsules per day. Although the
inclusion of the fish oil diluent helps improve absorption of the
CoQ10, it is still recommended that you take the capsules with meals.
Some people feel immediate benefits; others notice results after
6 to 8 weeks.
- Close tightly after opening and store in a cool, dry, dark place
(70-75 °F; 20.1-23.8 °C). Do not refrigerate.
- If pregnant or nursing, consult a health practitioner.
- Diabetics should consult a health practitioner.
Q & A
Why should I take AIM CellSparc 360®?
- Studies have found that as we age, our bodies cannot produce
CoQ10 as efficiently and its supply diminishes. It is important
to keep adequate levels of CoQ10 in our bodies. However, finding
healthy food sources of CoQ10 can be difficult. The best sources
of CoQ10 are animal muscle tissues, but many people prefer not to
eat this type of food. The CoQ10 in AIM CellSparc 360® is produced
from plant sources. Using it provides a way of maintaining the body’s
level of CoQ10 without compromising other dietary considerations.
Can I take more than the suggested amount?
- AIM CellSparc 360® is nontoxic, so larger amounts are acceptable,
depending on your assessment of your nutritional needs.
Why must I store AIM CellSparc 360® in a cool, dry, dark place?
- Because the CoQ10 used in AIM CellSparc 360® is so pure, it
has a relatively low melting temperature. This will not hurt the
efficacy of the product. However, heat, humidity, and sunlight could
cause the softgels to stick together.
References
- Albert, C.M., et al. “Fish Consumption and Risk of Sudden Cardiac
Death.” Journal of the American Medical Association 279 (1998):
23-28.
- Bucher, H.C., et al. “N-3 [Omega-3] Polyunsaturated Fatty Acids
in Coronary Heart Disease: A Meta-Analysis of Randomized Controlled
Trials.” American Journal of Medicine 112, no. 4 (2002): 298-304.
- Greenberg, A., and W. Frishman. “Coenzyme Q10: A New Drug for
Cardiovascular Health.” Journal of Clinical Pharmacology 30, no.
7 (July 1990): 596-608.
- Langsjoen, P., P. Langsjoen, R. Willis, and K. Folkers. “Treatment
of Essential Hypertension with Coenzyme Q10.” Molecular Aspects
of Medicine 15 Suppl (1994): S265-272.
- Qureshi, A.A., et al. “Dose-Dependent Suppression of Serum Cholesterol
by Tocotrienol-Rich Fraction (TRF(25)) of Rice Bran in Hypercholesterolemic Humans.” Atherosclerosis 161, no. 1 (2002): 199-207.
- Serbinova, E.A., and L. Packer. “Antioxidant Properties of Alpha-Tocopherol
and Alpha-Tocotrienol.” Methods Enzymol. 234 (1994): 354-366.
- Tran, M.T., et al. “Role of Coenzyme Q10 in Chronic Heart Failure,
Angina, and Hypertension.” Pharmacotherapy 21, no. 7 (2001): 797-806.
Benefits & Features
Benefits
- Helps maintain cardiovascular health
- Helps maintain healthy triglyceride levels
- Helps maintain healthy cholesterol levels
- Helps maintain gum health
- Increases energy production at the cellular level
- Potent antioxidant
- Quick absorption into the bloodstream
Features
- More than six years of safe and beneficial use by
AIM Members
- Unique formula contains 60 mg of coenzyme Q10, 100
mg of tocotrienols, and 240 mg of fish oil per softgel
capsule
- Japanese source of coenzyme Q10
- Coenzyme Q10 derived from a plant source
- No harsh solvents used in coenzyme Q10 extraction
process
- Softgel delivery system means quicker absorption
- 30-softgel capsules
AIM CellSparc 360® is a Cardio Health product. The complete
Cardio Health line consists of AIM CellSparc 360® and AIM
Bear Paw Garlic®. Use these products to help yourself maintain
cardiovascular health.
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